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New glaucoma drugs?

Question:

Hubert Mak wrote: > I guess you already try one or more of these eyedrops(drugs). Why you > need more?  It will benefit to all readers in this group if you > can post your experience with these eyedrops(drugs). > Thanks in advance. > ——————————————————–

Good suggestion. In random order, Pilocarpine does a decent job on pressure but constricts the pupil to the point where not much light comes through, making vision quite dim in the eye in which it’s used–also, there are cautions about possibly causing cataracts. Timoptic (and Cosopt since the same drug is in it) also does a good job on pressure, but tends to reduce respiratory capacity in a person with an asthma history, and seems to affect urination. Cosopt also seems good with pressure, but is irritating to me and has the Timoptic effects, plus I’m concerned about the other ingredients affect of red blood cells since I have a family history of anemia. Xalatan, again, is good with pressure but I’m starting to get some discoloration of my eyelids, and notable iris darkening. Alphagan and AlphaganP are good on pressure, but are very difficult for me to use as my eyes get quite red, burning and itching. Both Travatan and Lumigan made my eyes feel unbearably uncomfortable and had to be discontinued rather quickly. Currently I’m using Xalatan at night, and Cosopt night and morning. Hope this information is helpful to you, and others.

Response:

I guess you already try one or more of these eyedrops(drugs). Why you need more?  It will benefit to all readers in this group if you can post your experience with these eyedrops(drugs). Thanks in advance. ——————————————————– On 19 Mar 2005 halt…@aol.com wrote: – Hide quoted text — Show quoted text -> I wonder what the newest glaucoma medications might be. I am familiar > with Alphagan, AlphaganP, Travatan, Lumigan, Cosopt and the older > Timoptic, Pilocarpine, but wonder if there are any more recent ones > that have been helpful with POAG. > Thanks

Response:

Tom wrote: > I havent heard of the urination problem with timoptic.  What is that?  Also, > I am not sure if timoptic has > effect on red blood cells although it certainly has > an effect on the heart.

"Urination difficulties" is listed on the package insert with timolol maleate. Carbonic anhydrase inhibitors (a Cosopt ingredient) are reported to accululate in red blood cells and possibly affect blood cells in a manner similar to sulfonamids.

Response:

. Xalatan, again, is > good with pressure but I’m starting to get some discoloration of my > eyelids, and notable iris darkening.

I sometimes feel like I’m pouring lemon juice in my eyes with Xalatan and other times no stinging at all? Anyone know why this is? Al C.

Response:

"Al C." <crankinh…@optusnet.com.au> wrote in news:42513911$0$5190$afc38c87@news.optusnet.com.au: > . Xalatan, again, is >> good with pressure but I’m starting to get some discoloration of my >> eyelids, and notable iris darkening. > I sometimes feel like I’m pouring lemon juice in my eyes with > Xalatan and other times no stinging at all? Anyone know why this is? > Al C.

Al, Never had any pain problems with Xalatan (Trusopt was another story!)   Not sure why the stinging would be inconsistent like that though. You could try putting a lubricant drop in about 10-15 min before using the Xalatan (no sooner – you don’t want to dilute the Xalatan!) Sherry

Response:

<halt…@aol.com> wrote in message

news:1111347968.366030.276320@f14g2000cwb.googlegroups.com… – Hide quoted text — Show quoted text -> Hubert Mak wrote: > > I guess you already try one or more of these eyedrops(drugs). Why you > > need more?  It will benefit to all readers in this group if you > > can post your experience with these eyedrops(drugs). > > Thanks in advance. > > ——————————————————– > Good suggestion. In random order, Pilocarpine does a decent job on > pressure but constricts the pupil to the point where not much light > comes through, making vision quite dim in the eye in which it’s > used–also, there are cautions about possibly causing cataracts. > Timoptic (and Cosopt since the same drug is in it) also does a good job > on pressure, but tends to reduce respiratory capacity in a person with > an asthma history, and seems to affect urination. Cosopt also seems > good with pressure, but is irritating to me and has the Timoptic > effects, plus I’m concerned about the other ingredients affect of red > blood cells since I have a family history of anemia. Xalatan, again, is > good with pressure but I’m starting to get some discoloration of my > eyelids, and notable iris darkening. Alphagan and AlphaganP are good on > pressure, but are very difficult for me to use as my eyes get quite > red, burning and itching. Both Travatan and Lumigan made my eyes feel > unbearably uncomfortable and had to be discontinued rather quickly. > Currently I’m using Xalatan at night, and Cosopt night and morning. > Hope this information is helpful to you, and others.

I havent heard of the urination problem with timoptic.  What is that?  Also, I am not sure if timoptic has effect on red blood cells although it certainly has an effect on the heart.

Response:

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