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ICE Syndrome

Question:

I.C.E. =  Iridocorneal Endothelial Symptoms:  - usually asymptomatic, but you may notice abnormal iris/pupil appearance                     –  may cause blurred vision or pain in one eye                     – usually in young to middle-aged adults. Signs:    - corneal endothelial changes                - possible corneal edema               – increased intraocular pressure leading to glaucomatous optic nerve head changes and visual field loss               – typically unilateral ( if bilateral, may be asymmetric in presentation)               – peripheral anterior synechiae ( adhesions of the iris to the back of the cornea) Iris changes then will fit it into one of the following classifications: 1. Essential Iris Atrophy:     Iris thinning often leading to hole formation and displacement and distortion of the pupil. 2. Chandler’s Syndrome:     Mild iris thinning and pupil distortion.  Corneal changes more significant. 3. Cogan-Reese Syndrome:     Pigmented nodules on the iris surface with variable iris atrophy. It is not a heritable condition. Off the top of my head, I can’t remember the cause or proposed mechanism…. Treatment: None, unless glaucoma or corneal edema (swelling) is present. If either,or both are present: 1. Anti-glaucoma medications. &/or 2. Medications to reduce corneal swelling &/or Further glaucoma treatments (surgical) may be required if drops are ineffective and corneal transplant may be a consideration if corneal swelling is advanced and chronic. Fonou wrote: > Does anyone have Essential Iris Atrophy?  Can’t seem to fine much info on it.

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Response:

Does anyone have Essential Iris Atrophy?  Can’t seem to fine much info on it.

Response:

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